The Bursa of Fabricius and Antibody Production

Transfer of Antibody Production with Cells from Bursa of Fabricius

F(1) hybrid chicks isogenic for the strong B histocompatibility locus and for most weak H-loci were X-irradiated on day 1 after hatching, injected intraperitoneally on day 2 with dispersed cells of bursa, spleen, or thymus from 4- or 10-wk-old F(1) hybrid donors, and immediately challenged by the same route with either Brucella abortus, sheep erythrocytes, or a mixture of both together. The agg...

The Thymus and the Bursa of Fabricius in Chickens

The effect of cyclephosphamide (Cy) on the thymus and the bursa of Fabricius in chickens, aged one day to 7 weeks, was examined morphologically, Chiekens, which were daily injected i.m. with 6mg Cy 1, 2, or 3 times from the hatching day, were compared with saline coutrel chickens, The relative weights of both the thymus and the bursa decreased abruptly just after the injection of Cy. The weight...

Ephrin Receptor Expression in the Embryonic Bursa of Fabricius

Utilizing degenerate PCR primers complementary to conserved regions within the kinase domain of Receptor Tyrosine Kinase (RTK) genes, the goal was to compare the full complement of RTK expressed (mRNA level) between two developmental stages of bursal B-cells. We identified 21 different RTK cDNAs out of a total of 235 cDNAs sequenced between the two B-cell stages. The dataset revealed the expres...

The structure of the bursa of Fabricius in wild birds.

B. Glick et all,2 found that the antibody-producing ability is markedly re duced when the bursa of Fabricius (abbreviated as BF) of the newly-hatched chick is removed. Thus the function of this organ which is specific for birds received a great deal of attention. With the comparative study of bursectomy and thymectomy, it has been ascertained that the BF and the thymus play distinctive roles in...

Morphology of bursa of Fabricius in bursectomized and thymectomized ducks.